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Description Paroxetine is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, generalized anxiety disorder (GAD), social anxiety disorder (also known as social phobia), premenstrual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD). Brisdelle® is used only to treat moderate to severe hot flashes caused by menopause. Paroxetine belongs to a group of … Doctors may prescribe Paxil for depression or other conditions. This article provides an overview of Paxil, including its uses, side effects, and warnings. Compare paroxetine prices, print discount coupons, find manufacturer promotions, copay cards and patient assistance programs. PAROXETINE (pa ROX e teen) treats depression, anxiety, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). It increases the amount of serotonin in the brain, a hormone that helps regulate mood. It belongs to a group of medications called SSRIs. 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